Discovering Nuclease Escape Elements

escape cartoon

Related Publications:

Muller M, Hutin S, Marigold O, Li KH, Burlingame A, Glaunsinger BA.  2015.  A ribonucleoprotein complex protects the interleukin-6 mRNA from degradation by distinct herpesviral endonucleasesPLoS pathogens. 11(5):e1004899.

Hutin S, Lee Y, Glaunsinger BA.  2013.  An RNA element in human interleukin 6 confers escape from degradation by the gammaherpesviral SOX proteinJournal of virology. 

Clyde K, Glaunsinger BA.  2011.  Deep sequencing reveals direct targets of gammaherpesvirus-induced mRNA decay and suggests that multiple mechanisms govern cellular transcript escapePloS one. 6(5):e19655.

Glaunsinger B, Ganem D.  2004.  Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesisThe Journal of experimental medicine. 200(3):391-8.